哈佛大學公衛學院學者自1986年至2010年,追蹤近5萬名40至75歲男性的健康狀況,其中1/4受訪者曾接受輸精管結紮手術。調查發現,5萬名男性中有6023人被診斷出罹患攝護腺癌,其中811人癌病過世。經統計,結紮過的男性罹患攝護腺癌機率較一般人高10%,而發展成末期癌症甚至致死的機率也分別高出20%及19%。此研究刊登於《臨床腫瘤學期刊》(Journal of Clinical Oncology)。
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